Change to 1g amoxicillin PO dose
IVOS empirical choice added
5 days and review
Mild to Moderate infection
Amoxicillin oral 1g 8 hourly (or IV 1g 8 hourly if oral route not available)
+
Metronidazole oral 400mg 8 hourly (or 500mg IV 8 hourly if oral route not available)
Penicillin allergy
Doxycycline oral 200mg stat on first day then 100mg daily
(or vancomycin IV if oral route not available. Dosing as per guideline. Use Vancomycin calculator)
+
Metronidazole oral 400mg 8 hourly (or IV 500mg 8 hourly if oral route not available)
Severe Infection
Amoxicillin IV 1g 8 hourly
+
Metronidazole IV 500mg 8 hourly
+
Gentamicin IV (Extended interval dosing as per guideline. Use Gentamicin calculator. Max 3 days then review)
Severe Infection with Penicillin Allergy
Vancomycin IV (Dosing as per guideline. Use Vancomycin calculator)
+
Metronidazole IV 500mg 8 hourly
+
Gentamicin IV (Extended interval dosing as per guideline. Use Gentamicin calculator. Max 3 days then review)
Amoxicillin PO 1g 8 hourly
+
Metronidazole PO 400mg 8 hourly
or
Doxycycline PO 200mg stat on first day then 100mg PO daily
+
Metronidazole PO 400mg 8 hourly
Antimicrobial prescribing: NHS Borders