Antimicrobial prescribing: NHS Borders
Flucloxacillin IV 2g 6 hourly
+
Ciprofloxacin IV 400mg 12 hourly (IV for first dose then review if appropriate to switch patient to oral)
+
Clindamycin IV 600mg - 1.2g 6 hourly
Necrotising Fasciitis
Warning
Necrotising fasciitis
- Refer to Critical Care Outreach team
- Urgent surgical referral. Surgical treatment is the definitive treatment - antibiotics are an adjunct.
- Discuss with microbiology
- Require admission until infected area is clinically improving, systemic signs of infection are resolving, and co-morbidities stabilised.
Fluroquinolones
Refer to important safety information for all quinolones prior to prescribing.
See MHRA Drug Safety Update January 2024: Fluoroquinolones must only be used in situations when other antibiotics, that are commonly recommended for the infection, are inappropriate such as:
- there is resistance to other first-line antibiotics recommended for the infection
- other first-line antibiotics are contraindicated in an individual patient
- other first-line antibiotics have caused side effects in the patient requiring treatment to be stopped
- treatment with other first-line antibiotics has failed
Vancomycin (according to vancomycin dosing guideline -aim trough 15-20mg/L)
+
Ciprofloxacin IV 400mg 12 hourly (IV for first dose then review if appropriate to switch patient to oral)
+
Clindamycin IV 600mg - 1.2g 6 hourly