Submandibular Space Infections

Antimicrobial prescribing: NHS Forth Valley
NHS Forth Valley

First Line

Therapy

Co-amoxiclav 1.2g IV 8 hourly

Notes:

ADD Gentamicin IV (as per online calculator) if systemic infection/sepsis evidence on admission or deterioration

Mild Penicillin Allergy (e.g. rash)

Therapy

Ceftriaxone 2g IV 24 hourly AND Metronidazole 400mg PO 8 hourly

Notes:

ADD Gentamicin IV (as per online calculator) if systemic infection/sepsis evidence on admission or deterioration

Severe Penicillin Allergy (i.e. anaphylaxis, angioedema, urticaria, respiratory distress)

Therapy

Vancomycin IV (as per online calculator) AND Gentamicin IV (as per online calculator) AND Metronidazole 400mg PO 8 hourly 

Notes:

Notes

Incision & Drainage advised - send pus samples to microbiology.

ADD Fluconazole 400mg PO to empirical regime if yeasts reported on microscopy