Necrotising Fasciitis

Antimicrobial prescribing: NHS Forth Valley
NHS Forth Valley

First Line

Therapy

Benzylpenicillin 2.4 g IV 6 hourly AND Flucloxacillin 2g IV 6 hourly AND Clindamycin 1.2g IV 6 hourly AND Metronidazole 500mg IV 8 hourly AND Gentamicin IV (as per online calculator)

Notes:

Penicillin Allergy (or MRSA positive)

Therapy

Vancomycin IV (as per online calculator) AND Clindamycin 1.2g IV 6 hourly AND Metronidazole 500mg IV 8 hourly AND Gentamicin IV (as per online calculator)

Notes:

Notes

Characterised by pain disproportionate to clinical findings, rapidly spreading infection, dusky skin

SEEK URGENT SURGICAL REVIEW

Second line treatment based on advice from microbiology.

If evidence of toxic shock - consider IVIG