Impetigo
NICE Clinical Knowledge Summaries - Impetigo
Impetigo is usually a self-limiting infection which usually heals in 1-3 weeks without treatment
Impetigo is usually a clinical diagnosis, and investigations are not routinely needed.
Do not take a swab unless there widespread infection or failure/recurrence despite appropriate hygiene measures and empirical treatment as below.
Preferred treatments:
Localized non-bullous impetigo and not systemically unwell or at risk of complications: Hydrogen peroxide 1% cream
H2O2 not suitable OR widespread non-bullous impetigo and not systemically unwell/at risk of complications: Topical Fusidic acid (Mupirocin is another topical treatment option if suspected/confirmed Fusidic acid resistance)
Localised/widespread lesions but more systemically unwell OR bullous impetigo: Oral antibiotic
Adults and children aged 2 years or older with minor skin infection can be referred to their local community pharmacy for topical fusidic acid treatment.
Drug details
Hydrogen Peroxide 1% Cream
Apply TDS
5 days
Topical Fusidic Acid 2%
Apply TDS
5 days
Flucloxacillin
500mg QDS
Child
1 month to 1 year: 62.5mg to 125mg QDS
2 to 9 years: 125mg to 250mg QDS
10 to 17 years: 250mg to 500 mg QDS
5 days
Penicillin Allergy:
Doxycycline
200mg STAT then 100mg OD
5 days
Age <12yr old with
penicillin allergy:
Clarithromycin
Under 8 kg - 7.5mg/kg BD
8 to 11 kg - 62.5mg BD
12 to 19 kg: 125mg BD
20 to 29 kg - 187.5mg BD
30 to 40 kg - 250mg BD
5 days