NICE Clinical Knowledge Summaries - Infected eczema

Episodes of infected eczema usually co-exist with a flare and will require concomitant treatment

In people who are not systemically unwell, do not routinely offer either a topical or oral antibiotic for secondary bacterial infection of eczema.

Take into account:

  • The limited benefit of antibiotics in addition to topical corticosteroids compared with topical corticosteroids alone
  • The risk of antimicrobial resistance with repeated courses of antibiotics
  • The extent and severity of symptoms or signs
  • The risk of developing complications, which is higher in people with underlying conditions such as immunosuppression

 

Do not take a swab unless there is history of frequent recurrence of infected eczema

If after consideration antibiotic felt indicated:

  • Localized areas of infection and systemically well: Topical Fusidic acid
  • More widespread infection or systemically unwell: Oral antibiotic

Drug details

Topical Fusidic Acid 2%

Apply TDS

5 days

Flucloxacillin

Adult

500mg QDS

Child

1 month to 1 year: 62.5mg to 125mg QDS

2 to 9 years: 125mg to 250mg QDS

10 to 17 years: 250mg to 500 mg QDS

5 days

Penicillin allergy:

Doxycycline

 

200mg STAT then 100mg OD

 

5 days

Age <12yr old with

penicillin allergy:

Clarithromycin

 

 

1 month to 11 years:

Under 8 kg - 7.5mg/kg BD

8 to 11 kg - 62.5mg BD

12 to 19 kg: 125mg BD

20 to 29 kg - 187.5mg BD

30 to 40 kg - 250mg BD

 

 

5 days