Non Diabetic Leg Ulcer
Antibiotics do not improve healing unless active infection. (e.g. purulent exudate / odour, increased pain, cellulitis, pyrexia)
See Wound Management Guidelines and Formulary. (Page 71: Algorithm for assessment and management of chronic wounds)
Further information on wound assessment including a visual guide can be found here
Ulcers will always be colonised with bacteria e.g. Staph, coliforms (e.g. E coli, Proteus), Pseudomonas, anaerobes and possibly yeast too.
Do not take a swab unless there is evidence of ongoing/worsening infection despite appropriate wound management +/- empirical antibiotic. Swab must only be taken from AFTER cleaning and from deep within ulcer.
Effective chronic wound care is essential for healing and avoidance of recurrent infection.
Drug details
Flucloxacillin
500mg - 1g QDS
7 days
Penicillin allergy:
Doxycycline
200mg STAT followed by 100mg OD
7 days
Second Line:
Co-trimoxazole
960mg BD
7 days
If the infection is responding to antibiotic therapy but only slowly responding, review the patient after 7 days and consider continuing the antibiotic for a further 7 days.