Uncomplicated UTI - Men

Antimicrobial prescribing: NHS Grampian, Orkney & Shetland
NHS Grampian

Micro Organisms

Enterobacteriaceae spp.

Escherichia coli

Staphylococcus saprophyticus

Duration

7 days

Notes

Therapy

  • Uncomplicated UTI – ie no signs or symptoms of severe systemic infection
  • Samples should be taken prior to starting treatment.
  • Send blood for culture if pyrexial.
  • Send MSSU (carefully collected to avoid contamination.)
  • Do not treat asymptomatic bacteriuria (unless urological surgery)
  • Maintain adequate hydration – aim to drink 1.5L of water a day if no contraindications.
  • Review with microbiology results when available.

Notes:

Uncomplicated UTI - first line

Therapy

Trimethoprim oral 200mg twice daily for 7 days

Notes:

Uncomplicated UTI - 2nd line

Therapy

Cefalexin oral 500mg twice daily for 7 days

Notes:

Notes

  • Consider specialist referral for recurrent infection.
  • In patients with CKD3 or above and/or those at risk of hyperkalaemia trimethoprim may be unsuitable. Please check current prescribing advice as per BNF and seek specialist advice if alternative agent required.

Editorial Information

Last reviewed: 26/03/2026

Next review date: 26/03/2029

Author(s): Specialist Antimicrobial Pharmacists.

Version: 1

Author email(s): gram.antibioticpharmacists@nhs.scot.

Approved By: Antimicrobial Management Team

Document Id: AMT_Emp_Hosp_Uncomplicated UTI Men_1