Antimicrobial prescribing: NHS Lothian
Fidaxomicin 200mg every 12 hours orally
Duration = 10 days
Exception – treatment failure identified as incomplete treatment course. Treat as per first episode of CDI with vancomycin 125mg every 6 hours orally for 10 days.
Treatment of first recurrence of CDI
Warning
See Overview for overall care and management.
Treatment may not be required if the patient has an equivocal C. difficile result (see Equivocal result). If ongoing symptoms (e.g. diarrhoea), consider repeat testing and seek infection specialist advice as appropriate.
Review severity markers (see Severity of Infection) and contact infection specialist for advice (see How to get advice).
Treatment may not be required if the patient has an equivocal C. difficile result (see Equivocal result). If ongoing symptoms (e.g. diarrhoea), consider repeat testing and seek infection specialist advice as appropriate.
Review severity markers (see Severity of Infection) and contact infection specialist for advice (see How to get advice).
- For patients with mild, moderate or severe CDI as per treatment below.
- For life-threatening CDI as per Treatment of life-threatening infection.
Vancomycin 125 mg every 6 hours orally
Duration = 10 days