Diabetes prescribing guidance

Type 2 Diabetes Prescribing Guidance for Primary Care

Key Points:

  • Lifestyle is first-line therapy and important throughout care. Consider that diabetes remission is possible for some patients and refer patients to Adult weight management | Right Decisions
  • Newly diagnosed (within previous 12 months) patients with Type 2 diabetes should also be referred for structured education Control It via this referral form CONTROL IT REFERRAL.doc
  • Below is a link to an algorithm that is intended for individuals with above-target glycaemic control where escalation of therapy is indicated. It is not always necessary to modify therapy in individuals who are on regimens that include agents such as Gliclazide, Gliptins or Pioglitazone if glycaemic control is already at target, with no significant side effects, although clinicians may wish to consider if there are patients who might particularly benefit from the weight loss and cardiorenal risk reduction properties of the newer 2nd and 3rd line agents.

    – Link to Glucose Lowering Therapy Guidelines for Type 2 Diabetes (this is supplementary to the East Region Formulary) (To be advised, will be added to Refhelp in near future)

Diabetic Targets: Realistic Medicine, frailty, and personalised targets:

  • Although SIGN 2017 sets a target of 53mmol/mol for glycaemic control, targets should be individualised. NICE 2022 also recommends personalised targets and for some patients (where treatment is either lifestyle alone or on a single drug that does not cause hypoglycaemia (insulin and sulphonylureas) then a target of 48mmol may be appropriate.
  • Patient preference is important – some may be keen to take additional medication or may be reluctant because of the burden of polypharmacy and risks of intensive control.
  • Therapeutic targets should be modified in frail individuals. The table below is a summary of therapeutic targets from a UK expert consensus statement from the Foundation for Diabetes Research in Older People
Health Status Target HbA1c Target BP Lipid Modification
  Mmol/mol    

Healthy

Rationale: reasonable life expectancy
<58 140/90 Statins indicated

Intermediate Health

Several co-morbidities

Limited functional ability

Mild to moderate cognitive impairment

 

Rationale: intermediate life expectancy, high treatment burden (polypharmacy), vulnerable to hypoglycaemia and falls.
<64 140/90 Statins indicated

Poor Health

End-stage chronic

In long-term care/limited functional ability

Moderate to severe cognitive impairment

 

Rationale: limited life expectancy: benefits of treatment uncertain
<69 150/90 Benefits less certain: greater benefit in secondary prevention

Patient information leaflets containing:

 

Prescribing Information Formulary | East Region Formulary

 

Who to refer, who not to refer, how to refer

For referral guidance for people with diabetes please see Refhelp Diabetes diagnosis | Right Decisions

 

Primary care management

See above link to NHS Borders treatment and prescribing guidance for Type 2 diabetes

Resources and links

Patient information leaflets and Prescribing Information - see above

Editorial Information

Author(s): Rachel Williamson.

Author email(s): rachel.williamson@nhs.scot.