Carpometacarpal joint osteoarthritis (CMCJ)

Warning

The universal joint at the base of the thumb, between the metacarpal and trapezium bones, often becomes arthritic as people get older. It is osteoarthritis, which is loss of the smooth cartilage surface covering the ends of the bones in the joints. The cartilage becomes thin and rough, and the bone ends can rub together. Osteoarthritis can develop at any age, but usually appears after the age of 45. It may run in families, and it sometimes follows a fracture involving the joint many years before.

Arthritis of the basal joint of the thumb is common in women and rather less common in men. X-rays show it is present in about 25% of women over the age of 55, but many people with arthritis of this joint have no significant pain.

What are the symptoms?

  1. Pain at the base of the thumb, aggravated by thumb use.
  2. Tenderness if you press on the base of the thumb.
  3. Difficulty with tasks such as opening jars, turning a key in the lock etc.
  4. Stiffness of the thumb and some loss of ability to open the thumb away from the hand.
  5. In advanced cases, there is a bump at the base of the thumb and the middle thumb joint may hyperextend, giving a zigzag appearance

What is the treatment?

The options for treatment include:

  1. Avoiding activities that cause pain, if possible.
  2. Analgesic and/or anti-inflammatory medication. A pharmacist or your family doctor can advise.
  3. Using a splint to support the thumb and wrist. Rigid splints (metal or plastic) are effective but make thumb use difficult. A flexible neoprene rubber support is more practicable.
  4. Steroid injection improves pain in many cases, though the effect may wear off over time. The risks of injection are small, but it very occasionally causes some thinning or colour change in the skin at the site of injection. Improvement may occur within a few days of injection, but often takes several weeks to be effective. The injection can be repeated if needed.
  5. Surgery is a last resort, as the symptoms often stabilise over the long term and can be controlled by the non-surgical treatments above. There are various operations that can be performed to treat this condition.

Who to refer, who not to refer, how to refer

Who to Refer

  • Pain at base of thumb with weakness of grip not responding to non-operative treatment.

Urgent Referral Criteria

  • Nil

Who Not to Refer

  • Those who have not tried primary care management.

Additional Info

  • Specific tests – Pain on palpation of CMCJ at base of thumb +/- deformity and prominence of base of thumb metacarpal.

Imaging

  • Thumb Xray (Ideally < 1yr old)

How to refer

We accept referrals through SCI gateway for those who are based in Scotland.

We also accept e referrals through the below email address using the attached form for those who are based just on the other side of the border. 

E- Referral Email address - bor.orthoreferrals@borders.scot.nhs.uk

Referral form - E-Referral to Orthopaedics (Non Sci-Gateway)      

Primary care management

  • Patient Education ( See Patient Information leaflet in next section)
  • Rest / Activity modification
  • Oral +/- Topical NSAIDs (10% ibuprofen gel)
  • Actimove Rhizo Forte thumb splint
  • Push Ortho thumb brace
  • CSI 2-3 Person is trained and if possible

Resources and links

Editorial Information

Last reviewed: 31/07/2025

Next review date: 31/07/2027

Author(s): Mr Roshan Raghavan.

Author email(s): Roshan.Raghavan@nhs.scot.