DGRefHelp - NHS Dumfries & Galloway
- 100mg twice daily - avoid in eGFR<30 (Renal guidance)
Minocycline
Warning
Information for general practitioners
Updated 2026
The aim of treatment is to suppress disease activity and preserve joint function in the Inflammatory Arthropathies and other Rheumatic Disorders.
An Uncommonly used Drug in Rheumatoid Arthritis when Standard DMARDs are contraindicated or Ineffective/Not Tolerated
- Base line assessment only -FBC, U&E and LFT inc albumin
- Further blood monitoring is not required, though intermittent LFTs are advised
- Minocycline may take from 2-3 months, up to 1 year to be effective
- as per BNF - tetracyclines
Rare or very rare:
- acute CKD
- drug-induced SLE
- pigmentation
- neuropathy
- tinnitus
Secretaries 01387 241776
Helpline 01387 241095 (answering machine) Rheumatology Nurse Specialists
Department of Rheumatology doctors via Switchboard 01387 246246/RMS Advice