If the risk is not zero why doesn’t everyone take PEP?

Warning
  • PEP involves taking a combination of medicines for 28 days. These medicines can have side effects some of which are common and others which can be serious.
  • Common side effects include feeling sick, diarrhoea, dizziness, headaches and difficulty sleeping.
  • Serious side effects include rash and changes in liver and kidney function.
  • Most patients tolerate the medication well.
  • The patient will need baseline blood and urine tests and follow up which may include further visits and tests.

 

Editorial Information

Last reviewed: 20/04/2026

Next review date: 20/04/2028

Reviewer name(s): Soosan Romel.