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Genital Infections in Pregnancy (1247)

Warning

A guideline is intended to assist healthcare professionals in the choice of disease-specific treatments.

Clinical judgement should be exercised on the applicability of any guideline, influenced by individual patient characteristics. Clinicians should be mindful of the potential for harmful polypharmacy and increased susceptibility to adverse drug reactions in patients with multiple morbidities or frailty.

If, after discussion with the patient or carer, there are good reasons for not following a guideline, it is good practice to record these and communicate them to others involved in the care of the patient.

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Editorial Information

Last reviewed: 08/01/2026

Next review date: 10/03/2026

Author(s): Kay McAllister.

Version: 1

Author email(s): kay.mcallister2@nhs.scot.

Approved By: Sandyford Governance Group

Document Id: 1247

References

Brocklehurst P, Gordon A, Heatley E, Milan SJ. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database of Systematic Reviews 2013, Issue 1. Art. No.: CD000262. DOI: 10.1002/14651858.CD000262.pub4. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000262.pub4/full [Accessed March 2025] 

Safety of macrolide antibiotics in pregnancy: a review of the epidemiological evidence - GOV.UK (www.gov.uk) 

Joint British Association for Sexual Health and HIV and Royal College of Obstetricians and Gynaecologists national UK guideline for the management of herpes simplex virus (HSV) in pregnancy and the neonate (2024 update)

clarkeetal2024jointbritishassociationforsexualhealthandhivandroyalcollegeofobstetriciansand.pdf [Accessed March 2025] 

The West of Scotland Clinical Guidelines on Pregnancy and STI’s Guideline. Updates 2024.  Clinical Guidance – WOS Sexual Health MCN [Accessed March 2025] 

British Association of Sexual Health and HIV UK national guideline for the management of anogenital herpes, 2024 pateletal2024britishassociationofsexualhealthandhivuknationalguidelineforthemanagementofanogenital.pdf [Accessed March 2025] 

Joint British Association for Sexual Health and HIV and Royal College of Obstetricians and Gynaecologists national UK guideline for the management of herpes simplex virus (HSV) in pregnancy and the neonate (2024 update) clarkeetal2024jointbritishassociationforsexualhealthandhivandroyalcollegeofobstetriciansand.pdf [Accessed March 2025] 

British Association of Sexual Health and HIV (BASHH) UK guidelines for the management of syphilis in pregnancy and children 2024 syphilis_in_pregnancy_2024.pdf [Accessed March 2025]

UK National Guideline on the Management of Trichomonas vaginalis 2021 http://www.bashhguidelines.org/media/1310/tv-2021.pdf [Accessed March 2025] 

UK National Guidelines on the Management of infection Chlamydia Trachomatis 2015 https://www.bashhguidelines.org/media/1192/ct-2015.pdf  [Accessed March 2025] 

UK National Guidelines for the Management of Bacterial Vaginosis. 2012  https://www.bashhguidelines.org/media/1041/bv-2012.pdf

[Accessed March 2025] 

UK National Guidelines for the Management of Gonorrhoea. 2018 (updates 2020) https://www.bashhguidelines.org/media/1238/gc-2018.pdf

[Accessed March 2025]

British Association for Sexual Health and HIV National Guidelines for the Management of Vulvovaginal Candidiasis. 2019 https://www.bashh.org/_userfiles/pages/files/resources/vvc_ijsa_pdf.

[Accessed March 2025] 

British association for sexual health and HIV national guideline for the management of anogenital warts in adults (2024) agw_2024.pdf [Accessed March 2025] 

Interventions for trichomoniasis in pregnancy (Review) Gülmezoglu AM, The Cochrane Collaboration  https://www.cochrane.org/CD000220/PREG_interventions-for-trichomoniasis- in pregnancy  [Accessed March 2025] 

The Royal College of Obstetricians and Gynaecologists green top guideline Number 36 Third edition September 2017 ‘The Prevention of Early-onset Neonatal Group B Streptococcal Disease’ https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/prevention-of-early-onset-group-b-streptococcal-disease-green-top-guideline-no-36/ [Accessed March 2025]