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Mycoplasma Genitalium (1251)

A guideline is intended to assist healthcare professionals in the choice of disease-specific treatments.

Clinical judgement should be exercised on the applicability of any guideline, influenced by individual patient characteristics. Clinicians should be mindful of the potential for harmful polypharmacy and increased susceptibility to adverse drug reactions in patients with multiple morbidities or frailty.

If, after discussion with the patient or carer, there are good reasons for not following a guideline, it is good practice to record these and communicate them to others involved in the care of the patient.

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Editorial Information

Last reviewed: 14/01/2026

Next review date: 31/03/2026

Author(s): Kay McAllister.

Version: 1

Author email(s): kay.mcallister2@nhs.scot.

Approved By: Sandyford Governance Group

Document Id: 1251

References

BASHH Jan 2025. BASHH guideline for the management of infection with Mycoplasma genitalium see

ba02_guideline_mgen_public_cons_version_jan_2025.pdf

[accessed 11 March 2025]

BASHH Clinical Effectiveness Group. Response to MHRA statement on the use quinolone antimicrobials.Published 11/03/2024 . Available at Response to MHRA statement on the use quinolone antimicrobials | BASHH [accessed 11 March 2025]

Soni S, Horner P,  Rayment M et al.  2018 BASHH UK National guideline for the management of infection with mycoplasma genitalium. https://www.bashhguidelines.org/media/1228/mg-ijstdaids.pdf  [accessed 11 Mar 2025]

Jensen J.S, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M et al. European guideline on the management of Mycoplasma genitalium infections. First published: 19 February 2022 https://doi.org/10.1111/jdv.17972 [accessed 11 Mar 2025]

Medicines and Healthcare products Regulatory Agency. Fluoroquinolone antibiotics: must now only be prescribed when other commonly recommended antibiotics are inappropriate. Available at https://www.gov.uk/drug-safety-update/fluoroquinolone-antibiotics-must-now-only-be-prescribed-when-other-commonly-recommended-antibiotics-are-inappropriate [accessed 11 Mar 2025]

Pinto-Sander N, Soni S. Mycoplasma genitalium infection (Practice Pointer). BMJ 2019; 367:l5820 https://www.bmj.com/content/367/bmj.l5820  [accessed 11 Mar 2025, requires Athens]