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Gonorrhoea (Neisseria Gonorrhoea) CEG (961)

A guideline is intended to assist healthcare professionals in the choice of disease-specific treatments.

Clinical judgement should be exercised on the applicability of any guideline, influenced by individual patient characteristics. Clinicians should be mindful of the potential for harmful polypharmacy and increased susceptibility to adverse drug reactions in patients with multiple morbidities or frailty.

If, after discussion with the patient or carer, there are good reasons for not following a guideline, it is good practice to record these and communicate them to others involved in the care of the patient.

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Editorial Information

Last reviewed: 04/12/2025

Next review date: 30/11/2026

Author(s): Kay McAllister.

Version: 5

Author email(s): kay.mcallister2@nhs.scot.

Approved By: Sandyford Governance Group

Document Id: 961

References

Gonorrhoea management:

British Association for Sexual Health and HIV Clinical Effectiveness Group. (2025) UK National Guideline for the Management of infection with Neisseria gonorrhoeae, 2025. Available at: https://www.bashh.org/resources/136/gonorrhoea_2025_updated_guideline  [accessed on 19/09/2025]

Gonorrhoea antibiotic resistance:

Public Health Scotland (2025). Sexually transmitted infections in Scotland Available at: https://publichealthscotland.scot/media/33613/sexually-transmitted-infections-public-report_final.pdf [accessed on 19/09/2025]

Genital meningococcal disease

UK Health Security Agency (2024) Guidance for public health management of meningococcal disease in the UK  Available at: https://assets.publishing.service.gov.uk/media/673257250a2b4132b43d1448/UKHSA-meningo-disease-guidelines-november2024.pdf [accessed on 19/09/25]

West of Scotland Managed Clinical Network in Sexual Health Clinical Guidelines Group (2025) Appendix 2: Genital infection due to Neisseria meningitides  Available at: https://rightdecisions.scot.nhs.uk/west-of-scotland-sexual-health-clinical-guidelines-in-development/sexually-transmitted-infections-stis/gonorrhoea/appendix-2-genital-infection-due-to-neisseria-meningitidis/ [Accessed on 19/09/2025]

 

Medicines information:

NICE BNF (2025) Cefixime Available at: https://bnf.nice.org.uk/drugs/cefixime/

[accessed on 10/09/25]

Medicines and Healthcare products Regulatory Agency.  Fluoroquinolone antibiotics: must now only be prescribed when other commonly recommended antibiotics are inappropriate alerts about fluoroquinolone. 22/1/2024. Available at https://www.gov.uk/drug-safety-update/fluoroquinolone-antibiotics-must-now-only-be-prescribed-when-other-commonly-recommended-antibiotics-are-inappropriate [accessed on 19/09/2025]

Summary of Product Characteristics Ceftriaxone 1g powder for injection https://www.medicines.org.uk/emc/product/1361/smpc [accessed on 19/09/25]

Summary of Product Characteristics Gentamicin 40mgs/ml injection.  Gentamicin 40mg/ml Solution for Injection or Infusion - Summary of Product Characteristics (SmPC) - (emc) (medicines.org.uk)  [accessed 08/02/2024]