Newborn blood spot screening - update March 2026

The following documents describe the March 2026 changes to the Newborn Blood Spot Screening programme.

Main changes from previous version

  • Information on the In Service Evaluation (ISE) for Spinal Muscular Atrophy (SMA) that will be implemented from 23rd March 2026.
  • Healthcare professionals taking newborn bloodspot samples should ensure that parents are aware that SMA has been added to list of conditions screened for on a temporary, in-service evaluation basis
  • The ISE will be for an 18-24 month period

All staff delivering the newborn screening programme should ensure they are aware of a these updated requirements/clarifications on taking samples, the management of repeat samples and the management of “movers in” and cross border babies.