Hoarseness is a very common referral to ENT; it is the most common presenting feature of laryngeal carcinoma. It is important to be aware however that between 2-18% of lung cancers also present with hoarseness, with the incidence of lung cancer being 4:1 when compared to all head and neck cancers.
Non neoplastic causes of chronic hoarseness
- Chronic inflammation
- Trauma
- Infection
- Laryngopharyngeal reflux (LPR)
- Vocal overuse
- Neuromuscular or Neurological: MS, Parkinsonism, Myasthenia Gravis, Motor Neuron Disease etc
- Systemic: Rheumatoid Arthritis, Laryngeal Sarcoidosis, Amyloidosis, Granulomatosis with polyangitis
Important aspects to the history in primary care
- The key question is “can the voice be normal at any point” – if so then this is a routine referral
- Rule out other red flag symptoms (haemoptysis, referred unilateral otalgia,)
- Assess if any red flag respiratory symptoms potentially indicating a lung primary or metastasis
- Smoking and alcohol history
- PMH of asthma with inhaled corticosteroids or untreated reflux disease
Ascertain the onset and fluctuation/ fatigability of the symptoms
- Hoarseness first thing in the morning is likely to be reflux related
- Worsening throughout the day maybe neurological
- Progressive constant symptoms more likely to be sinister pathology
- Intermittent hoarseness is most likely to be of benign pathology
Physical examination
- Assess vocal quality, cough and swallow
- Examination of the neck and identify any lymphadenopathy
- Respiratory and neurological examination (tongue movement/palate lift/gag reflex) dependant on history and findings.
Throat care advice in general practice
- Avoid exposure to irritants – cigarette smoke, caffeine, alcohol, spicy or acidic foods
- Vocal overuse as well as repetitive throat clearing should be discouraged.
- A trial of PPI and Gaviscon advance TDS should be consider if symptoms of laryngopharyngeal reflux ONLY after strict lifestyle and dietary advice (download & explain to patient Silent Reflux Advice)