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Barrett’s Oesophagus

The oesophagus (food pipe/gullet) carries food from the mouth to the stomach and is lined by cells similar to that of the skin (squamous cells); these cells are pinkish-white and flat.

In Barrett’s oesophagus, the cells become tall and red (columnar cells).  These cells can also vary in appearance; some resemble the stomach lining, others that of the small intestine (intestinal metaplasia).

Causes

It is thought that long-term exposure of the oesophagus to acid reflux (gastro oesophageal reflux disease – GORD) causes Barrett’s oesophagus. The oesophagus does not have a protective lining against the acid produced in the stomach, therefore over exposure to this acid can cause inflammation and pain (oesophagitis). 

The oesophagus usually heals with time, but the abnormal cells develop as the lining heals after being damaged by the acid.  Overtime these changed cells can develop into something called ‘dysplasia’, which is a precancerous condition.

Not everyone with dysplasia will develop cancer, but it does increase the risk.

Symptoms

  • Heartburn
  • Acid reflux
  • Indigestion
  • Nausea
  • Difficulty and/or pain swallowing food.
  • Hoarse voice / chronic sore throat.
  • Upper abdominal pain.

Treatment

  • Acid-suppressant medication (PPI)
  • Surveillance
  • Surgery

Surveillance:

If you have Barrett’s you will sometimes be monitored closely by having regular endoscopies or a capsule sponge test.  The decision on how often to undertake surveillance is based on a discussion between the patient and the Consultant, length of Barrett’s segment, pathology results and health factors.

Sometimes people will be offered procedures that treat or remove the damaged segment of the oesophagus.

Surgery:

If this is seen as beneficial, you will be referred to a surgeon to discuss this.  Surgery can be performed to strengthen the valve at the bottom of the oesophagus to prevent further reflux, or to remove the abnormal cells.

Other treatments such as Radiofrequency Ablation (RFA) or Argon Plasma Coagulation may be considered for treatment of Barrett’s.

Lifestyle Changes:

  • Losing weight
  • Eating slowly / chewing well
  • Eating smaller meals more often than fewer larger meals
  • Not eating late at night
  • Stop smoking
  • Reduce alcohol intake
  • Reduce caffeine intake
  • Avoiding fizzy drinks
  • Elevating the head of the bed

Further Information:

https://gutscharity.org.uk/

Editorial Information

Next review date: 29/02/2028

Author(s): Clifford G.

Version: V1

Approved By: Acute Clinical Governance Board

Reviewer name(s): Graham K.