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  3. Polypharmacy guidance: Appropriate prescribing making medicines safe, effective and sustainable 2026-2029
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ManageMeds - polypharmacy

Case studies

Polypharmacy guidance: Appropriate prescribing making medicines safe, effective and sustainable 2026-2029
National

Frailty without overt multimorbidity

Frailty with multimorbidity

Care home resident with multimorbidity

Care home resident with multimorbidity including dementia

Younger adult with intellectual disability in a care home

Multimorbidity without frailty (acute pain, depression, COPD and high-risk combinations)

High risk combination – antiplatelet and anticoagulant

Chronic pain – opioids

Chronic pain – anticonvulsants

Chronic pain – antidepressants

Type 2 diabetes mellitus with severe frailty

Chronic constipation

Adult with Parkinson’s disease

Depression and health inequalities

Anxiety

Post traumatic stress disorder with “street benzo” use

Bipolar disorder and lithium

Antipsychotics in dementia

Antipsychotic use following recent hospital discharge

Antibiotics - penicillin allergy de-labelling

Antibiotics in end-of-life care

Medication sick day guidance (in nursing home resident)

Osteoporosis and risk of falls

Palliative care (Cardiovascular)

Palliative care – End of life care

Drug dependency and requests for medication out of hours

Addressing the use of psychoactive medication for people living with dementia through non-pharmacological techniques

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