Warning

Please see list of red flags

Assessment

Signs & symptoms

  • A persistent dull ache particularly around the spine, ribs or pelvis.
  • May cause bone fragility ( vertebral collapse)
  • Fatigue, weakness, breathlessness often caused by anaemia.
  • Repeated infections.
  • Extreme thirst, nausea, stomach pain, increased urination/ constipation (due to hypercalcaemia)
  • Blurred vision, headaches, dizziness.
  • Signs of kidney failure.
  • Calcium elevation with renal dysfunction, anaemia and backache/ bone pain (CRAB) do not all need to be present.

Risk factors

  • Men>women.
  • Adults over 60.
  • Black people affected> white or Asian people.
  • Family history of multiple myeloma.

When & how to refer

Referral to Haematology.

Editorial Information

Next review date: 01/10/2027

Author(s): Reid J.

Version: 01.0

Approved By: Trauma & Orthopaedics Acute Governance