p16 positive oropharyngeal squamous cell carcinoma (SCC) TNM

Clinical staging, p16 positive oropharyngeal tumours, TNM 8^th Edition, UICC, 2017

 

Primary Tumour (T)

T1        Tumours 2cm or less in greatest dimension

T2        Tumours greater than 2cm but not greater than 4cm in greatest dimension

T3        Tumour more than 4cm in dimension or extension into lingual surface of epiglottis

T4        Tumour invades any of the following: larynx, deep/extrinsic muscles of the tongue (genioglossus, hyoglossus, palatoglossus, and styloglossus), medial pterygoid, hard palate, mandible, lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, skull base or encases carotid artery

NB        Mucosal extension to the lingual surface of the epiglottis from primary tumours of the base of tongue or vallecula does not constitute invasion of the larynx

 

Regional Lymph Nodes (N)

Nx       Regional lymph nodes cannot be assessed

N0       No regional lymph node metastasis

N1       Unilateral metastasis, in lymph node(s), all 6cm or less in greatest dimension

N2       Contralateral or bilateral metastasis in lymph node(s) all 6cm or less in greatest dimension

N3       Metastasis in a node greater than 6cm in dimension

NB Midline nodes are considered ipsilateral

 

Distant Metastasis (M)

M0       No distant metastasis

M1       Distant metastasis

 

Pathological classification p16 positive oropharyngeal tumours, TNM 8^th Edition, UICC, 2017.

 

The pT categories correspond to the T categories

pNx     Regional lymph nodes cannot be assessed

pN0     No regional lymph node metastasis

pN1     Metastasis in 1 to 4 lymph node(s)

pN2     Metastasis in 5 or more lymph node(s)