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Pathway recommendations

Week 0

Prompt recognition, risk assessment and referral is essential to reduce any delay in diagnosis and to reduce the high proportion of lung cancer patients who are diagnosed via emergency admissions in Scotland.

The Scottish Referral Guidelines for Suspected Cancer support primary care clinicians in identifying patients who are most likely to have cancer and therefore require urgent assessment by a specialist. Equally, the Guidelines help in identifying patients who are unlikely to have cancer, embedding safety netting as a diagnostic support tool.

The Guidelines are clear that a normal chest x-ray does not exclude a lung cancer diagnosis. All GP practices in NHS Scotland have access to computed tomography (CT) Chest and CT Chest, Abdomen and Pelvis (CAP), via a Rapid Cancer Diagnostic Service (RCDS) or direct access referral.

A Chest X-Ray (CXR) is usually the first diagnostic test performed and this should happen quickly. When a CXR is normal or equivocal, a CT Chest may suffice to rule out lung cancer; where this is available this could be ordered by a GP and thus spare patients the worry associated with attending secondary care. Where a CXR is identified as abnormal, a full staging CT scan should be arranged promptly.

The pathway stipulates that within the first 3 days (maximum), patients with a suspicion of lung cancer will have had a CXR and CT scan acquired and reported. The CXR to CT pathway may be prioritised for implementation as it impacts on a larger volume of patients at the start of the pathway, and so in effect has a greater impact on all patients who will eventually be diagnosed with lung cancer.

 

Week 1

This stage of the pathway begins when the CT result is available. This, together with other available clinical information should provide sufficient details to enable a senior clinical decision maker to decide whether or not the patient enters a USC pathway or is discharged/redirected.

If results are suggestive of cancer, then the patient needs to be progressed urgently. The pathway recommends that a staging CT CAP (chest abdomen pelvis) is undertaken in the next 1-2 working days and hot reported.

Arrangements should be in place for prompt access to a cancer clinic – these should be reserved for patients where imaging results indicate a suspicion of cancer so that resources can remain focused on those most likely to have a cancer diagnosis.

Importantly, it’s at this stage that a navigator/ Single Point of Contact (SPOC) initiates contact with the patient to ensure they’re clear on next steps and have any questions or concerns allayed.

 

Week 2

All patients potentially suitable for curative treatment on the optimal diagnostic pathway will require a range of tests to be undertaken. This is likely to include at least a Positron Emission Tomography (PET) CT, often an endobronchial ultrasound (E-BUS)/bronchoscopy biopsy and may require detailed lung function tests. It may also include cardiac and exercise testing.

All tests need to happen by day 14, where possible, they should be ‘bundled’ and arranged within the same day for patient convenience and to minimise delay.

This part of the pathway outlines the ambition for PET CT scans to be hot reported.

 

Week 3

The pathway stipulates that histology turnaround times for the initial diagnostic report should happen within 5 days but additional molecular testing to guide targeted therapies, e.g. epidermal growth factor receptor (EGFR) gene mutation, anaplastic lymphoma kinase (ALK) gene rearrangement and programmed death-ligand 1 (PDL1) expression, will take longer - possibly a further 5 days.

There have been a number of publications produced on how an effective lung Multi-disciplinary Team Meeting (MDT) should function including the UK Lung Cancer Coalition’s review on the ‘Dream MDT’ and key principles outlined in the Framework for Effective Cancer Management.

As the pathway outlines - the ambition is for the patient to be informed of the outcome of the MDT on the same day with them and their families given time to understand and consider their treatment options and, if any, benefits and risks.

 

Weeks 4-6

By day 21 of the pathway, patients should jointly agree their treatment plan (decision to treat) with their clinical team.

To ensure that the referral for treatment happens as efficiently as possible, prompt notification to the treating specialist is required. This should include the results of pre-operative tests already performed such as lung function and biopsy reports.

Efficient use of time in planning complex radiotherapy treatment by oncologists, radiographers and physicists is necessary to reduce the time to curative-intent radiotherapy.

 

Best practice examples

NHS Borders

In NHS Borders, all patients referred as a USC are contacted by the Single Point of Contact (SPoC) team following vetting, to confirm that they have been added to a cancer pathway and are offered information (including a leaflet) to describe the support available. During the diagnostic phase of the pathway, patients can contact the SPoC team to discuss any concerns they or their friends/family may have.

If a cancer is diagnosed, patients are contacted by the SPoC team to offer screening for universal prehabilitation and are referred for completion of Holistic Needs Assessment.

 

NHS Lanarkshire

NHS Lanarkshire has developed and implemented two Advanced Nurse Practitioner (ANP)-led pathways to support Urgent Suspicion of Lung Cancer referrals. On completion of vetting, patients are appointed to the most suitable ANP clinic determined by chest radiographic appearance.

Patients with 'red flag' symptoms but without chest radiographic evidence of thoracic malignancy are appointed to a low-suspicion pathway, virtually managed to coordinate further diagnostic investigations. Where the chest radiograph is concerning for thoracic malignancy, patients are seen face-to-face for assessment and the necessary investigations requested.

In all cases, CT imaging results are discussed with a Respiratory Consultant to confirm the management plan, with outcomes including discharge, appointment to a lung cancer clinic (with PET-CT scan undertaken if indicated), appointment to a non-cancer respiratory clinic, or onward referral to another specialty. Results and outcomes are communicated directly to patients by the ANP.

These pathway changes have delivered significant benefits, including improved patient flow and patient experience through timely communication. In addition, the approach has optimised the use of Respiratory Consultant-led lung cancer clinic appointments ensuring capacity is prioritised for patients with the highest clinical need, reducing unnecessary face-to-face attendances, and supporting earlier diagnosis where thoracic malignancy is suspected.

 

NHS Tayside

When a suspicious chest x-ray is identified by Radiology, they immediately arrange a CT scan. An alert code triggers a notification to the cancer team with the patient’s GP copied. The patient is contacted by the hospital and a CT scan and urgent chest clinic appointment arranged for the earliest date.

 

NHS Ayrshire & Arran

In NHS Ayrshire & Arran, a virtual clinic takes place every Monday afternoon to review all those that have had a CT scan although the report doesn’t have to be ready. This is alternated each week between two Respiratory Consultants. Active Clinical Referral Triage (ACRT) is then undertaken and if lung cancer is suspected, patients will be seen in the weekly lung clinic to agree a diagnostic plan. A letter is issued to all patients not identified as high risk to manage their expectations and reduce anxiety as quickly as possible. This process enables around a third of patients to be discharged and ensures that clinic and any additional diagnostic capacity is efficiently used.

 

NHS Greater Glasgow & Clyde

Across the West of Scotland, 5 PET-CT slots per day are currently allocated for priority booking for lung cancer patients (who are fit and appropriate for radical treatment). The aim is for these patients to have PET-CT within 7-10 days of referral. Between March 2024 and March 2025, 671 referrals were received. 73% of patients referred for these slots had their scans and reports completed within 10 days (40% within 7 days). This has allowed these patients to progress more quickly along the optimal pathway and has had no noticeable effect on the waiting times for other cancers.

 

NHS Lothian

We have CT slots scheduled on the same day as clinic appointments. These are hot reported by radiology alongside the respiratory physician to allow planning for next steps and immediate relay of results to patients. Any unused CT slots can be used for inpatients to avoid waste. Also built around our clinic is our lung function service providing basic spirometry and protected full lung function tests (TCO/IWT) for radically treatable disease; capacity is extended at very short notice as required.

The ethos of our service has been 'why wait', trying to minimise pathway days with no activity. Assisting with this, our radiologists will email all radiology concerning for lung cancer allowing us to liaise urgently with GPs and triage to our service rapidly. This frequently leads to a 1 day turnaround between abnormal CXR and patients attending a CT or clinic appointment. Every step and day matters so it may feel like a particular initiative may only improve the pathway by 2 or 3 days but the cumulative effect will be impactful. We will guarantee that those services within our control can be offered within 7 days, e.g. time from abnormal CXR to diagnostic CT/clinic, time from referral with CT to clinic, time to endobronchial ultrasound/bronchoscopy. We have taken a pan-Lothian approach in sharing and creating capacity for this.

The major advance in our pathways has been the introduction of our next day scheduled PET-CT service. After auditing the number of PET-CT requests and understanding how many were crucial to the next diagnostic test i.e. endobronchial ultrasound following stage 2/3 disease where lymph nodes staging was required, the PET team agreed to 2 scheduled PET-CT slots the day following our lung cancer clinic (trialled at a single site). It adds another step in an administrative heavy pathway for the clinician but the impact has been tremendous. This has now been extended to the other sites in NHS Lothian. Allowing 2 working days for a PET-CT report allows us to schedule endobronchial ultrasound, where appropriate, the day after report. Most patients not on this accelerated PET-CT pathway are on a different pathway i.e. growing nodules so are not disadvantaged.

 

Accelerated National Innovation Adoption (ANIA) Pathway

NHS Grampian and NHS Greater Glasgow and Clyde have been piloting the use of AI technology to accelerate the diagnosis of suspected lung cancer from chest x-rays (CXRs).

Building on this work, and as part of the Accelerated National Innovation Adoption (ANIA) Pathway, a Value Case is in development which aims to accelerate the diagnosis of lung cancer following a GP requested CXR by the national deployment of this pathway enhancement. This will see CXRs identified by the AI technology as ‘high risk’ and reported speedily (Scotland’s optimal lung cancer diagnostic pathway says within 72 hours) with diagnostic CTs taking place within the subsequent 72 hour period.

 

NHS Scotland Academy

The National Bronchoscopy and Endobronchial Ultrasound (EBUS) Training Programme, offered by the NHS Scotland Academy, has been developed to improve lung cancer outcomes for patients across Scotland. The programme delivers training in basic bronchoscopy, endobronchial ultrasound and transbronchial needle aspiration of mediastinal lymph nodes.

The programme is being delivered over a 3 year period and will train 45 respiratory trainees in basic bronchoscopy, and approximately 40 senior trainee consultants in endobronchial ultrasound and transbronchial needle aspiration. Further information on the programme and how to apply can be found here.

 

Our best practice examples are continually being reviewed and updated. If you have any examples you would like us to share, please contact us to discuss. Equally if you would like any further information on the examples above, please contact us at cfsdcancerandedteam@nhs.scot

 

Further resources

Framework for Effective Cancer Management (2025) - https://www.gov.scot/publications/framework-effective-cancer-management-2/

Detect Cancer Earlier (DCE) Programme (Lung) - https://getcheckedearly.org/lung-cancer

Scottish Referral Guidelines for Suspected Cancer (Lung and pleural cancers) - https://rightdecisions.scot.nhs.uk/scottish-referral-guidelines-for-suspected-cancer/lung-and-pleural-cancers/

Urgent Suspicion of Cancer: national regrading guidance (2023) - https://www.gov.scot/publications/urgent-suspicion-cancer-national-regrading-guidance/

Centre for Sustainable Delivery’s High Impact Changes (incl. ACRT) - https://www.nhscfsd.co.uk/our-work/modernising-patient-pathways/high-impact-changes/

Centre for Sustainable Delivery’s Respiratory Specialty Delivery Group -  https://www.nhscfsd.co.uk/our-work/modernising-patient-pathways/specialty-delivery-groups/respiratory/

National Prehabilitation for Scotland - https://www.prehab.nhs.scot/

Key Principles for Implementing Cancer Prehabilitation across Scotland - https://www.prehab.nhs.scot/for-professionals/key-principles/

Macmillan Principles and Guidance for Prehabilitation Within The Management and Support of People with Cancer - https://www.macmillan.org.uk/healthcare-professionals/news-and-resources/guides/principles-and-guidance-for-prehabilitation

Nutrition Framework for People Affected by Cancer - https://www.prehab.nhs.scot/wp-content/uploads/Published-Nutrition-Framework-Nov-2022-1.pdf

Psychological therapies and support framework for people affected by cancer - https://www.prehab.nhs.scot/wp-content/uploads/Psychological-therapies-and-support-framework-for-people-affected-by-cancer-April-2022.pdf

Single Point of Contact (SPOC) scalability assessment - https://www.healthcareimprovementscotland.scot/publications/scalability-assessment-for-single-point-of-contact-for-cancer-care-march-2025/

 

 

  cfsdcancerandedteam@nhs.scot

  www.nhscfsd.co.uk

@NHSScotCfSD

Centre for Sustainable Delivery

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Editorial Information

Last reviewed: 31/03/2025

Next review date: 31/12/2028

Author(s): The Centre for Sustainable Delivery.