Regimens, documentation, and follow up

Warning

Starting regimens for POP

Ensure client understands the method to aid satisfaction and compliance, and knows to take one tablet daily at the same time. Discuss methods such as phone reminders to support regular pill taking.

1. No extra precautions required if starting:

  • Day 1 to 5 of the cycle (day 1 for DRSP POP)
  • Up to 21 days postpartum; lactation is not affected
  • Days 1 to 5 post-termination or miscarriage (day 1 for DRSP POP)
  • While taking combined pill: change by instant switch (that is, without the COC pill-free interval)
  • While using injectable contraception, POP should be started at least 2 days before the next injection is due at 14 weeks after previous injection. (7 days for DRSP POP)
  • With intrauterine contraception, IUS or implant in situ (within licence limit).
    Remove the IUS/IUD/implant at least 48 hours after starting the POP (7 days for DRSP POP).

2. POP may be started at any time in the cycle if it is reasonably certain that the client is not pregnant, using additional contraceptive precautions for two days (7 days for DRSP POP).

3. A POP started immediately after ulipristal emergency contraception (UPA-EC) could potentially reduce the effectiveness of the UPA-EC. The POP should be started 5 days after UPA-EC is taken. See WoS Emergency Contraception guideline.

Vomiting and diarrhoea

Gastrointestinal upsets, such as vomiting or severe diarrhoea, may interfere with the absorption of the pill leading to a reduction in contraceptive efficacy.

Follow missed pill rules if vomiting occurs within a few hours of pill taking (see manufacturer instructions below) or if severe diarrhoea persists for >24 hours 5,7.

Manufacturer advice

Desogestrel: vomiting within 3-4 hours of taking tablet : follow missed tablet advice8

Norgeston®: vomiting within 2 hours of taking tablet: another pill should be taken as soon as possible. If a replacement pill is not taken within 3 hours follow missed pill advice. Persistent vomiting and/or very severe diarrhoea: use additional barrier contraceptive during the illness and for 7 days after recovery3

Noriday®: Women should continue to take Noriday and use another contraceptive method during the period of vomiting/diarrhoea and for the next 7 days9

Slynd®: vomiting or diarrhoea within 3-4 hours after tablet taking, take another tablet as soon as possible and within 24 hours of the usual time of tablet-taking. If more than 24 hours elapse, follow missed pill advice

Documentation

  • Complete or update the relevant parts of NaSH.
  • Give written method information including contact number to client.
  • Record and date the prescription in NaSH.
  • If supply is under patient group direction, complete relevant documentation as local protocol.
  • For new starts, notify the GP if permission has been given for correspondence.

Follow up arrangements

Return visit

Women may be offered up to 12 months of POP at her first and subsequent visit, with follow up yearly to ensure satisfaction and concordance with the method. Thereafter, there should be a flexible approach to contraceptive supply with ease of access should problems arise.

Editorial Information

Last reviewed: 30/06/2025

Next review date: 30/06/2027

Author(s): West of Scotland Managed Clinical Network for Sexual Health Clinical Guidelines Group.

Version: 10.3

Approved By: West of Scotland Managed Clinical Network for Sexual Health

Reviewer name(s): George Laird.