Warning

Catastrophic External Haemorrhage

  • Use simple dressings with direct pressure to control external haemorrhage.
  • In patients with major limb trauma use a tourniquet if direct pressure has failed to control haemorrhage.
  • It may be appropriate to use a tourniquet first line in some situations.  A second tourniquet is sometimes required.  Check the tourniquet after patient movement and consider replacing with a pneumatic tourniquet following resuscitation.

Airway with C-spine Control

  • Use basic manoeuvres, suction and adjuncts if airway compromise
  • Use drug assisted RSI to secure the airway.
  • If RSI fails, use basic manoeuvres and adjuncts and/or supraglottic device to oxygenate until:
    • either a surgical airway or 
    • assisted tracheal placement is performed.
  • Maintain in-line stabilisation of neck if mechanism or clinical findings suggest cervical spine risk or injury.

Breathing

  • Perform CXR and/or eFAST in all patients with haemodynamic instability or severe respiratory compromise.
  • Decompress the chest using an open thoracostomy followed by intercostals chest drain insertion. 
  • Perform immediate CT in other patient with significant chest injury.
  • Open pneumothorax -> Apply chest seal and then insert chest drain
  • Massive haemothorax -> Insert chest drain and monitor output. May require theatre if large output
  • Flail chest and respiratory distress -> consider intubation and ventilation for ventilator failure

Paediatrics - immediate chest CT is not indicated in children with a normal CXR chest examination.

Circulation and haemorrhage control

  • Look for the ‘Hateful Eight’ signs of exsanguinating haemorrhage to help identify patients likely to be in haemorrhagic shock. These signs are an expert-based clinical tool, not a validated scoring system
    • Pale
    • Clammy
    • ‘Air Hunger’
    • Venous collapse
    • Hypotension (low volume or absent peripheral pulses)
    • Low/falling ETCO2
    • Tachycardia or relative bradycardia
    • Altered mentation
  • Stop the bleeding
    • External: as above
    • Internal: Damage control surgery, interventional radiology or other definitive interventions
  • Vascular access
    • Two large bore IV lines are first-line
    • If IV is difficult or time-critical, place an intraosseous line.
    • Central access (e.g. subclavian, femoral) may be needed
  • Haemorrhage control is the priority.  Titrate volume to a central pulse.
  • Permissive hypotension
    • For penetrating torso trauma, consider keeping SBP ~80-90 mmHg until bleeding is controlled
    • Avoid if TBI is the priority or if the hypotensive period exceeds ~ 1hour
    • No permissive hypotension in paediatrics
  • Fluids & Blood products
    • Minimise crystalloids; favour balanced blood product transfusion
    • Start with a fixed-ratio protocol for blood components and change to lab/ROTEM/VBG guided once available
    • TXA as per local guidance
    • Keep the patient warm. Use under-patient bair hugger for enhanced and code red trauma calls. Ensure fluids or blood are warmed with Ranger or Belmont.
  • Vasopressers?
    • Generally avoid in haemorrhagic shock, as they do not address the root cause (blood loss) and may reduce organ perfusion
    • Exceptions include:
      • Neurogenic shock with bradycardia and vasodilatation
      • Cardiogenic or mixed shock states
      • TBI where maintaining a higher MAP is crucial for cerebral perfusion, but only after haemorrhage control is underway
  • Imaging
    • Limit imaging to CXR, Pelvis XR and FAST in patients not adequately responding to volume to direct early surgical intervention.
    • A negative FAST does not exclude intraperitoneal or retroperitoneal haemorrhage.
    • Use immediate CT in haemodynamically normal patients/volume responders

Bleeding mimics

Not all hypotension or shock in trauma stems purely from haemorrhage. Common mimics include:

  • Tension pneumothorax
  • Cardiac tamponade
  • Neurogenic shock
  • Cardiogenic shock

Please also refer to the NICE guidelines on

Major trauma: initial assessment and management.

Tranexamic Acid (TXA)

The following adults should receive 1g TXA *

    • At risk of bleeding or with confirmed bleeding and a HR >110 and/or SBP <90mmHg
    • GCS<13 with evidence of a head injury 
  • Give a further 1g bolus if there is:
    • bleeding requiring ongoing resuscitation and/or haemorrhage control
    • confirmed intracranial haemorrhage in patients with GCS <13
    • hyperfibrinolysis on viscoelastic studies

*Do not give first dose of TXA >3hours from injury unless evidence of hyperfibrinolysis. 

The maximum total dose is 2g. 

Where all criteria are met it may be appropriate to administer a 2g bolus

Paediatrics: permissive hypotension should not be used in paediatric trauma patients. 

Disability 

  • Use intravenous morphine 1st line (5mg aliquots, reduced in elderly).
  • Use intravenous ketamine 2nd line (0.2-0.5mg/kg).
  • Consider intranasal ketamine if IV access not established (0.7mg/kg).
  • Correct hypoglycaemia

Environment

  • Fully undress but prevent hypothermia
  • Use fluid warming devices, warm blankets and a BAIR HUGGER in all major trauma patients where haemorrhage is suspected or proven.
  • Hypothermia -> coagulopathy -> worsened bleeding

Paediatrics

Please also refer to the Royal College of Radiologist's guidelines for guidance on paediatric trauma.

Definitive Care

Involve specialty consultants (Orthopaedics, Vascular, IR and General Surgery) ensuring joint decision making regarding the following definitive care principles:

  • Consider damage control surgery in patients with instability who do not adequately respond to volume.
  • Use definitive surgery in haemodynamically normal patients.
  • Consider IR in patients with active arterial pelvic haemorrhage unless open surgery required for other injuries.
  • Consider IR in patients with solid organ arterial haemorrhage (spleen, liver or kidney).
  • Consider a joint IR/Surgical strategy for inaccessible regions.
  • Consider an endovascular stent for patients with blunt thoracic aortic injury.

Paediatrics: Paediatric morphine dose (IV) is 0.05 - 0.1mg/kg 

Editorial Information

Last reviewed: 01/04/2025

Next review date: 01/04/2028

Version: 2.0