- Use simple dressings with direct pressure to control external haemorrhage.
- In patients with major limb trauma use a tourniquet if direct pressure has failed to control haemorrhage.
- It may be appropriate to use a tourniquet first line in some situations. A second tourniquet is sometimes required. Check the tourniquet after patient movement and consider replacing with a pneumatic tourniquet following resuscitation.
Primary survey key principles
Catastrophic External Haemorrhage
Airway with C-spine Control
- Use basic manoeuvres, suction and adjuncts if airway compromise
- Use drug assisted RSI to secure the airway.
- If RSI fails, use basic manoeuvres and adjuncts and/or supraglottic device to oxygenate until:
- either a surgical airway or
- assisted tracheal placement is performed.
- Maintain in-line stabilisation of neck if mechanism or clinical findings suggest cervical spine risk or injury.
Breathing
- Perform CXR and/or eFAST in all patients with haemodynamic instability or severe respiratory compromise.
- Decompress the chest using an open thoracostomy followed by intercostals chest drain insertion.
- Perform immediate CT in other patient with significant chest injury.
- Open pneumothorax -> Apply chest seal and then insert chest drain
- Massive haemothorax -> Insert chest drain and monitor output. May require theatre if large output
- Flail chest and respiratory distress -> consider intubation and ventilation for ventilator failure

Circulation and haemorrhage control
- Look for the ‘Hateful Eight’ signs of exsanguinating haemorrhage to help identify patients likely to be in haemorrhagic shock. These signs are an expert-based clinical tool, not a validated scoring system
- Pale
- Clammy
- ‘Air Hunger’
- Venous collapse
- Hypotension (low volume or absent peripheral pulses)
- Low/falling ETCO2
- Tachycardia or relative bradycardia
- Altered mentation
- Stop the bleeding
- External: as above
- Internal: Damage control surgery, interventional radiology or other definitive interventions
- Vascular access
- Two large bore IV lines are first-line
- If IV is difficult or time-critical, place an intraosseous line.
- Central access (e.g. subclavian, femoral) may be needed
- Haemorrhage control is the priority. Titrate volume to a central pulse.
- Permissive hypotension
- For penetrating torso trauma, consider keeping SBP ~80-90 mmHg until bleeding is controlled
- Avoid if TBI is the priority or if the hypotensive period exceeds ~ 1hour
- No permissive hypotension in paediatrics
- Fluids & Blood products
- Minimise crystalloids; favour balanced blood product transfusion
- Start with a fixed-ratio protocol for blood components and change to lab/ROTEM/VBG guided once available
- TXA as per local guidance
- Keep the patient warm. Use under-patient bair hugger for enhanced and code red trauma calls. Ensure fluids or blood are warmed with Ranger or Belmont.
- Vasopressers?
- Generally avoid in haemorrhagic shock, as they do not address the root cause (blood loss) and may reduce organ perfusion
- Exceptions include:
- Neurogenic shock with bradycardia and vasodilatation
- Cardiogenic or mixed shock states
- TBI where maintaining a higher MAP is crucial for cerebral perfusion, but only after haemorrhage control is underway
- Imaging
- Limit imaging to CXR, Pelvis XR and FAST in patients not adequately responding to volume to direct early surgical intervention.
- A negative FAST does not exclude intraperitoneal or retroperitoneal haemorrhage.
- Use immediate CT in haemodynamically normal patients/volume responders
Bleeding mimics
Not all hypotension or shock in trauma stems purely from haemorrhage. Common mimics include:
- Tension pneumothorax
- Cardiac tamponade
- Neurogenic shock
- Cardiogenic shock
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Please also refer to the NICE guidelines on Major trauma: initial assessment and management. |
Tranexamic Acid (TXA)
The following adults should receive 1g TXA *
-
- At risk of bleeding or with confirmed bleeding and a HR >110 and/or SBP <90mmHg
- GCS<13 with evidence of a head injury
- Give a further 1g bolus if there is:
- bleeding requiring ongoing resuscitation and/or haemorrhage control
- confirmed intracranial haemorrhage in patients with GCS <13
- hyperfibrinolysis on viscoelastic studies
*Do not give first dose of TXA >3hours from injury unless evidence of hyperfibrinolysis.
The maximum total dose is 2g.
Where all criteria are met it may be appropriate to administer a 2g bolus
Disability
- Use intravenous morphine 1st line (5mg aliquots, reduced in elderly).
- Use intravenous ketamine 2nd line (0.2-0.5mg/kg).
- Consider intranasal ketamine if IV access not established (0.7mg/kg).
- Correct hypoglycaemia
Environment
- Fully undress but prevent hypothermia
- Use fluid warming devices, warm blankets and a BAIR HUGGER in all major trauma patients where haemorrhage is suspected or proven.
- Hypothermia -> coagulopathy -> worsened bleeding
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Paediatrics Please also refer to the Royal College of Radiologist's guidelines for guidance on paediatric trauma. |
Definitive Care
Involve specialty consultants (Orthopaedics, Vascular, IR and General Surgery) ensuring joint decision making regarding the following definitive care principles:
- Consider damage control surgery in patients with instability who do not adequately respond to volume.
- Use definitive surgery in haemodynamically normal patients.
- Consider IR in patients with active arterial pelvic haemorrhage unless open surgery required for other injuries.
- Consider IR in patients with solid organ arterial haemorrhage (spleen, liver or kidney).
- Consider a joint IR/Surgical strategy for inaccessible regions.
- Consider an endovascular stent for patients with blunt thoracic aortic injury.
Editorial Information
Last reviewed: 01/04/2025
Next review date: 01/04/2028
Version: 2.0