Important: Formulation and dosage details
Formulation:
Injection 150mg/mL (aqueous suspension) (Depo-Provera®)
Dosage:
By deep intramuscular injection, 150mg within first 5 days of cycle or within first 5 days after parturition; for long-term contraception repeat every 13 weeks (if interval greater than 14 weeks, rule out pregnancy before next injection and advise additional contraceptive measures for 7 days after the injection) off-label refer to FSRH Clinical Guideline: Progestogen-only Injectable.
Important: Formulation and dosage details
Formulation:
Suspension for injection 104mg/0·65mL (Sayana Press®)
Dosage:
By subcutaneous injection, 104mg within first 5 days of cycle, the second and subsequent doses should be given at 13 week intervals; for further information refer to SPC.
Notes:
- Sayana Press® is administered by the subcutaneous route.
- Rather than attending a clinic every 13 weeks for an injection, a woman can choose to self-administer Sayana Press® at home.
- Women must be trained in the technique and supervised by an appropriately trained health care professional (HCP) administering the first dose.
- Up to three injections may be given to take home with review at one year.
- Access to a HCP should be available if any problems arise.
- Give patients written information detailing administration instructions, potential side-effects and symptoms that should prompt medical review: https://highlandsexualhealth.co.uk/application/files/1317/3771/7466/sayana-press-a-guide-to-self-injection.pdf.
- Systems should be in place for the provision and disposal of sharps.
- Additional information: SAYANA Package leaflet.
- Further information for HCP can be found on the FSRH website: FSRH Clinical Guideline: Progestogen-only Injectables (December 2014, amended July 2023) | FSRH.
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Patient information can be accessed via NHS Inform: Contraceptive injection | NHS inform.
- See also Sayana Press.
