For red flag symptoms, see www.nice.org.uk/guidance/ng1
Infant Feeding Difficulties Clinic & Paediatric Infant Feeding Allergy Clinic (Paediatric Guidelines)
Warning
What's new / Latest updates
21/08/25:
- Information on normalising crying behaviour in babies added.
- Medication choices have been added. These have been reviewed and simplified from previous guideline 'PPI selection & administration in children', which is now archived.
- Patient information leaflets have been added for omeprazole and lansoprazole.
Audience
- North NHS Highland
- Primary and Secondary only
- Children only
Normalise behaviour in first instance
- Provide Crying and Your Baby leaflet (includes signposting to online resources)
- Refer to Health Visitor team for additional support
- Refer to Crying and Your Baby Webinar (Further info available from yvonne.sutherland5@nhs.scot)
Normalise regurgitation in first instance
- If only symptom is regurgitation, offer reassurance to parent that this can be normal for a baby to regurgitate.
- Feeding assessment may be required as per below.
Assessment of GOR
Indicators of GOR include:
- Unexplained feeding difficulties (refusing to feed, gagging, choking)
- Faltering growth
- Chronic cough and or hoarseness
- Single episode of pneumonia
Feeding assessment: Formula fed
Ensure feeding is paced & responsive:
- Feed to around 150mL/kg/day (1oz = 28mL) & try small, frequent feeds.
Symptoms suggestive of GOR (See to NICE NG1): consider trial of thickener
- Start at: ½ scoop of Carobel for every 90mL/3oz of feed.
If there is no improvement, then increase to 1 scoop to 1 ½ scoops per 90mL/3oz of feed. - If there is no improvement after a 2 week trial then refer to IFDC via paediatric dietetics: paediatricdietitians@highland.gov.uk
If ONLY symptom is overt regurgitation, do NOT treat with PPI
Feeding assessment: Breast fed
- Ensure a full breastfeeding assessment is carried out by an appropriately trained Health Care Professional, ensuring positioning and attachment has been assessed as effective
- If any concerns: Refer to specialist breastfeeding service via nhsh.specialistbreastfeedingclinic@nhs.scot
Symptoms suggestive of GOR (See to NICE NG1): consider trial of thickener
- Gaviscon Infant or Cow & Gate Instant Carobel.
For Carobel give as a paste before feeding. 3 scoops to 2oz EBM - If there is no improvement after a 2 week trial then refer to IFDC via paediatric dietetics: paediatricdietitians@highland.gov.uk
Non-IgE CMPA
- See NICE CKS cows-milk-allergy-in-children/diagnosis/diagnosis/
- Non-IgE is a delayed reaction (2 to 72hrs)
Symptoms
- Pruritus / erythema / flushing / atopic eczema
- Regurgitation +/-reflux
- Gastrointestinal symptoms: Eg, loose / frequent stools (can be normal in breastfed infants), blood, mucus in stools, constipation, straining (even with soft stools), abdominal pain or discomfort colic / irritability, perianal redness
- Oral aversion
- Pallor / tiredness
- Faltering growth, with at least one GI symptom
- Respiratory symptoms (cough, wheeze, SOB) plus at least one symptom from above
Breast fed
- Refer to specialist Breastfeeding Service via nhsh.specialistbreastfeedingclinic@nhs.scot
Formula fed
If non-IgE mediated CMPA is suspected
- Start 3 week trial of an Extensively Hydrolysed Formula (EHF) (Eg, Aptamil Pepti Syneo).
- After 3 weeks: re-challenge back to standard formula.
- If symptoms resolve on EHF & reoccur on re-challenge: continue with EHF & immediately refer to IFAC via paediatric dietetics: paediatricdietitians@highland.gov.uk
If IgE mediated CMPA is suspected. Eg: Hives / swelling:
- Start EHF and refer immediately to dietetics.
- DO NOT RE-CHALLENGE
- If symptoms do not resolve with EHF prior to seeing dietetics: Some infants don’t tolerate Carobel & symptoms can be similar to CMPA.
If not tolerating EHF & also using Carobel, please stop Carobel first before move to Amino Acid Formula (AAF) Eg, Neocate Syneo) - Dietetics to review.
- AAF - Amino Acid Formula
- CMPA - Cow’s milk protein allergy
- EHF - Extensively Hydrolysed Formula
- GI - gastrointestinal
- GOR - gastro-oesophageal reflux
- GORD - Gastro-oesophageal reflux disease
- SOB - shortness of breath